McMMAF
McMMAF is a protective group-conjugated MMAF. MMAF is a potent tubulin polymerization inhibitor.It is a MMAF derivative having a Maleimidocaproyl linker (MC linker), which is ready to conjugate to antibody or other proteins or biopolymers. Mafodotin is a useful agent for make antibody drug conjugate (ADC) for targeted drug delivery.
Product Specifications
CAS Number
863971-19-1
Product Name Alternative
Maleimidocaproyl monomethylauristatin F
Purity
>98% (HPLC)
Solubility
DMSO:100 mg/mL (108.09 mM)
Smiles
O=C (O) [C@H] (CC1=CC=CC=C1) NC ([C@H] (C) [C@H] ([C@H]2N (C (C[C@@H] (OC) [C@@H] (N (C) C ([C@@H] (NC ([C@@H] (N (C) C (CCCCCN3C (C=CC3=O) =O) =O) C (C) C) =O) C (C) C) =O) [C@@H] (C) CC) =O) CCC2) OC) =O
Molecular Formula
C49H76N6O11
Molecular Weight
925.16
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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