Leptomycin B
Leptomycin B is a potent inhibitor of the nuclear export of proteins and is a potent antifungal antibiotic blocking the eukaryotic cell cycle. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue.
Product Specifications
CAS Number
87081-35-4
Product Name Alternative
CI 940 | LMB
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : ≥ 100 mg/mL (184.94 mM)
Smiles
CC/C (/C=C/[C@@H] ([C@@H] (C) C=C1) OC1=O) =C/[C@H] (C) C/C=C/C (/C) =C/[C@@H] (C) C ([C@@H] (C) [C@@H] ([C@@H] (C) C/C (/C) =C/C (O) =O) O) =O
Molecular Formula
C33H48O6
Molecular Weight
540.73
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Available Sizes
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