Shield-1
Shield-1 is a specific, high-affinity and cell-permeant ligand of FK506-binding protein-12 (FKBP), and reverses the instability by binding to mutated FKBP (mtFKBP), allowing conditional expression of mtFKBP-fused proteins. Shield-1 can stabilize the entire fusion protein.
Product Specifications
CAS Number
914805-33-7
Purity
>98% (HPLC)
Solubility
DMSO:250 mg/mL (333.82 mM)
Smiles
O=C ([C@H]1N (C ([C@H] (C2=CC (OC) =C (OC) C (OC) =C2) CC) =O) CCCC1) O[C@@H] (C3=CC=CC (OCCN4CCOCC4) =C3) CCC5=CC=C (OC) C (OC) =C5
Molecular Formula
C42H56N2O10
Molecular Weight
748.9
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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