PAR4 antagonist 5
PAR4 antagonist 5 (compound 1) is a PAR4 antagonist with an IC50 less than 20 μM and potent anti-platelet aggregation activity. PAR4 antagonist 5 can be used for research of thrombosis disease [1].
Product Specifications
CAS Number
[3024653-17-3]
UNSPSC
12352005
Target
Protease Activated Receptor (PAR)
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/par4-antagonist-5.html
Solubility
10 mM in DMSO
Smiles
COC1=CC2=C(N=C(C3=C4N=NC(OC)=CC4=CC(C)=C3)S2)C(Cl)=C1
Molecular Formula
C18H14ClN3O2S
Molecular Weight
371.84
References & Citations
[1]Zhu X, et al. Preparation of cinnoline derivatives as PAR4 antagonists for prevention and/or treatment of thromboembolic disorders, China, CN117285527 A, 2023-12-26
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PAR4
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