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PAR4 antagonist 5

Product Specifications

UNSPSC Description

PAR4 antagonist 5 (compound 1) is a PAR4 antagonist with an IC50 less than 20 μM and potent anti-platelet aggregation activity. PAR4 antagonist 5 can be used for research of thrombosis disease [1].

Target Antigen

Protease Activated Receptor (PAR)

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/par4-antagonist-5.html

Solubility

10 mM in DMSO

Smiles

COC1=CC2=C(N=C(C3=C4N=NC(OC)=CC4=CC(C)=C3)S2)C(Cl)=C1

Molecular Weight

371.84

References & Citations

[1]Zhu X, et al. Preparation of cinnoline derivatives as PAR4 antagonists for prevention and/or treatment of thromboembolic disorders, China, CN117285527 A, 2023-12-26

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-163504/PAR4-antagonist-5-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-163504/

Clinical Information

No Development Reported

CAS Number

3024653-17-3

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