15-Lipoxygenase Inhibitor 1
15-Lipoxygenase Inhibitor 1 is a selective inhibitor of 15-lipoxygenase, with an IC50 of 18 μM. 4-MMPB has IC50s of 19.5 μM and 19.1 μM for soybean 15-lipoxygenase (SLO) and human 15-lipoxygenase-1 (15-LOX-1), respectively. 4-MMPB has potential for the research of prostate cancer. (In Vitro) :4-MMPB has an IC50 of 69.6 μM for DPPH bleaching.4-MMPB exhibits cytotoxic activity on human PC-3 and HFF3 cell lines.4-MMPB (41.48 μM; 72 hours) induces apoptosis and DNA damage in PC-3 Cells.
Product Specifications
CAS Number
928853-86-5
Product Name Alternative
4-MMPB
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
DMSO:8mg/mL (25.52mM)
Smiles
CC1=C2C (=NC (=N1) N3CCN (CC3) C) SC4=CC=CC=C4N2
Molecular Formula
C16H19N5S
Molecular Weight
313.4
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Available Sizes
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