Acuitas Lipid A9
Lipid A9 is an ionizable cationic lipid (pKa = 6.27) that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA and siRNA in vivo. LNPs containing lipid A9 and encapsulating non-stimulatory siRNA increase plasma levels of chemokine (C-C motif) ligand 2 (CCL2), indicating activation of the innate immune response, and decrease body weight in mice.
Product Specifications
CAS Number
2036272-50-9
Field of Research
Metabolism Research
Purity
>95%
Smiles
CCCCCCCCC (=O) N (CCCN (C) C) C (CCCCCCCCC (=O) OCC (CCCC) CCCCCC) CCCCCCCCC (=O) OCC (CCCC) CCCCCC
Molecular Formula
C57H112N2O5
Molecular Weight
905.51
Notes
For research use only.
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