PLX5622 hemifumarate
PLX-5622 hemifumarate is a highly selective brain penetrant and orally active CSF1R inhibitor (IC50=0.016 μM; Ki=5.9 nM) . PLX5622 hemifumarate allows for extended and specific microglial elimination, preceding and during pathology development. PLX5622 hemifumarate demonstrates desirable PK properties in varies animals.
Product Specifications
Purity
>98%
Smiles
CC1=CN=C (NC=C2CC3=C (F) N=C (NCC4=CC (F) =CN=C4OC) C=C3) C2=C1.O=C (O) /C=C/C (O) =O.CC5=CN=C (NC=C6CC7=C (F) N=C (NCC8=CC (F) =CN=C8OC) C=C7) C6=C5
Molecular Formula
C23H21F2N5O3
Molecular Weight
453.45
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNCB1154-100 1x 100 µL
Mucin 3 (MUC3/1154), Biotin conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
AP01368PU-N 100 µg
PI 3 Kinase p85 alpha (PIK3R1) (alpha/gamma) Rabbit Polyclonal Antibody
Sign In for Pricing
View Details 
