Y 39983HCl
Y-39983, also known as Y-33075, is a potent and selective inhibitor of ROCK family with IC50 value of 3.6nM for ROCK. Y-39983 attenuates experimental autoimmune encephalomyelitis via inhibition of demyelination. Y-39983 downregulates RhoA/Rho-associated kinase expression during its promotion of axonal regeneration. Y-39983, promotes regeneration of crushed axons of retinal ganglion cells into the optic nerve of adult cats.
Product Specifications
CAS Number
471843-75-1
Purity
>98%
Smiles
Cl[H].O=C (C1C ([H]) =C ([H]) C (=C ([H]) C=1[H]) [C@@] ([H]) (C ([H]) ([H]) [H]) N ([H]) [H]) N ([H]) C1C ([H]) =C ([H]) N=C2C=1C ([H]) =C ([H]) N2[H]
Molecular Formula
C16H17ClN4O
Molecular Weight
316.789
Notes
For research use only.
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