IGP-1

Product Specifications

CAS Number

27031-00-1

Field of Research

Cell Biology

Purity

>98%

Bioactivity

Mitochondrial glyceraldehyde-3-phosphate dehydrogenase inhibitor

Form

Powder

Solubility

Soluble in DMSO up to 50 mg/ml

Molecular Formula

C17H415N3O3

Molecular Weight

309.3

Storage Conditions

-20°C

Notes

For research use only.

Applications Notes

A potent and cell permeable inhibitor of the mitochondrial glycerol-3-phosphate dehydrogenase (mGPDH), IC50=6.3 M, which is selective over the cytosolic enzyme1. It does not block pyruvate uptake into cells or mitochondria and has no direct effect on glycolysis in synaptosomes. This novel inhibitor is a unique tool which may be used to investigate the role of glycerol-3-phosphate metabolism in isolated and intact systems.