Actinonin
Actinonin ((-) -Actinonin) is a naturally occurring antibacterial agent produced by Actinomyces. Actinonin inhibits aminopeptidase M, aminopeptidase N and leucine aminopeptidase. Actinonin is a potent reversible peptide deformylase (PDF) inhibitor with a Ki of 0.28 nM. Actinonin also inhibits MMP-1, MMP-3, MMP-8, MMP-9, and hmeprin α with Ki values of 300 nM, 1,700 nM, 190 nM, 330 nM, and 20 nM, respectively. Actinonin is an apoptosis inducer. Actinonin has antiproliferative and antitumor activities.
Product Specifications
CAS Number
13434-13-4
Field of Research
Cell Biology
Purity
>98%
Bioactivity
Leucyl aminopeptidase inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 20 mg/ml) .
Smiles
CCCCCC (CC (=O) NO) C (=O) NC (C (C) C) C (=O) N1C (CO) CCC1
Molecular Formula
C19H36N3O5
Molecular Weight
385.51
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
3-[[1-[-2-Hydroxymethyl) -1-pyrrolidinyl) carbonyl]-2-methylpropyl]carbamoyl]-octanohydroxamic acid
Available Sizes
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