SU-909
SU-909 (SU909, IKKα-IN-48) is a potent, selective IKKα inhibitor with Ki of 0.08±0.07 uM, 10-20-fold selectivity over IKKβ (IC50=1.0±0.28 uM) ; inhibits FCS-stimulated phosphorylation of p100 in U2OS cells with IC50 of 8.8 uM, inhibits the noncanonical NF-kB pathway without affecting IKKβ-dependent IKappa-Bα loss in the canonical pathway.
Product Specifications
CAS Number
2126749-48-0
Purity
>98%
Smiles
S (C1C=CC (=CC=1) C1=C2C (C#N) =CNC2=NC (N) =N1) (N) (=O) =O
Molecular Formula
C13H10N6O2S
Molecular Weight
314.322499752045
Notes
For research use only.
More Discoveries
Explore Other Products
Browse additional items from our catalog
227657 100 µg
FCGRT (IgG Receptor FcRn Large Subunit p51, IgG Fc Fragment Receptor Transporter Alpha Chain, FCRN) (FITC)
Sign In for Pricing
View Details 