SU-909
SU-909 (SU909, IKKα-IN-48) is a potent, selective IKKα inhibitor with Ki of 0.08±0.07 uM, 10-20-fold selectivity over IKKβ (IC50=1.0±0.28 uM) ; inhibits FCS-stimulated phosphorylation of p100 in U2OS cells with IC50 of 8.8 uM, inhibits the noncanonical NF-kB pathway without affecting IKKβ-dependent IKappa-Bα loss in the canonical pathway.
Product Specifications
CAS Number
2126749-48-0
Purity
>98%
Smiles
S (C1C=CC (=CC=1) C1=C2C (C#N) =CNC2=NC (N) =N1) (N) (=O) =O
Molecular Formula
C13H10N6O2S
Molecular Weight
314.322499752045
Notes
For research use only.
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