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DSR-141562

DSR-141562 is a novel, orally active, and selective brain-penetrant phosphodiesterase 1 (PDE1) inhibitor. DSR-141562 shows preferential selectivity for human PDE1B with an IC50 of 43.9 nM, and the IC50 values for human PDE1A and 1C are 97.6 and 431.8 nM, respectively. DSR-141562 can be used for the study of positive symptoms, negative symptoms and cognitive impairments associated with schizophrenia.

Product Specifications

CAS Number

2007975-22-4

Purity

>98%

Smiles

O=C1N (C) C (OC[C@H]2CC[C@H] (C (F) (F) F) CC2) =NN3C1=CN=C3C4CCOCC4

Molecular Formula

C19H25F3N4O3

Molecular Weight

414.42

Notes

For research use only.

Available Sizes

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