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ML359

ML359 is a small molecule, specific inhibitor of Protein disulfide isomerase (PDI) with IC50 of 250 nM; displays > 100-fold selectivity over other thiol isomerases (Erp5, Thioredoxin, Thioredoxin reductase) ; shows no cytotoxicity in three human cell lines, and some activity in inhibiting platelet aggregation in vitro.

Product Specifications

CAS Number

1069858-99-6

Purity

>98%

Smiles

O1C=CC=C1C (N (CC) C1C2=CC3C=CC (=CC=3N=C2N (C) N=1) OC) =O

Molecular Formula

C19H18N4O3

Molecular Weight

350.371223926544

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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