PD-1/PD-L1-IN 3
PD-1/PD-L1-IN 3, a macrocyclic peptide, is a potent and selective inhibitor of the PD-1/PD-L1 and CD80/PD-L1 interactions extracted from patent WO2014151634A1, compound No.1. PD-1/PD-L1-IN 3 interferes with PD-L1 binding to PD-1 and CD80 by binding to PD-L1, with IC50s of 5.60 nM and 7.04 nM, respectively. PD-1/PD-L1-IN 3 can be used for the research of various diseases, including cancer and infectious diseases.
Product Specifications
CAS Number
1629654-95-0
Field of Research
Cancer Biology; Immunology & Inflammation
Purity
>98%
Smiles
O=C (N ([C@H] (C (N ([C@H] (C (N[C@H] (C (N[C@] (CSCC (N[C@H] (C (N ([C@H] (C (N[C@H] (C (N1CCC[C@]1 (C (N[C@] ([H]) (C (N[C@H] (C (N (CC (N[C@H] (C (N[C@H] (C2=O) CO) =O) CC3=CNC4=CC=CC=C34) =O) C) =O) CC (C) C) =O) CC5=CN=CN5) =O) [H]) =O) CC (N) =O) =O) C) C) =O) CC6=CC=CC=C6) =O) ([H]) C (NCC (N) =O) =O) =O) CC
Molecular Formula
C89H126N24O18S
Molecular Weight
1852.17
Notes
For research use only.
Available Sizes
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