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UNC6852

UNC6852 is a selective rolycomb repressive complex 2 (PRC2) degrader based on PROTAC and contains an EED (embryonic ectoderm development) ligand and a VHL ligand, with an IC50 of 247 nM for EED.

Product Specifications

Purity

>98%

Smiles

O=C (NCCCC (=O) N[C@@H] (C (C) (C) C) C (=O) N1C[C@H] (O) C[C@H]1C (=O) NCC1C=CC (C2SC=NC=2C) =CC=1) C1C=CC (C2C3=NN=CN3C (NCC3OC=CC=3) =NC=2) =CC=1

Molecular Formula

C43H48N10O6S

Molecular Weight

832.969627380371

Notes

For research use only.

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