VU 0465350
VU 0465350 is a potent, specific BMP receptor activin receptor-like kinase 3 (ALK3) antaognist with Ki of 92.3 nM; shows no activity for ALK2/4/5, also shows affinity for TGFBR2, VEGFR2 and AMPK; blocks SMAD phosphorylation in vitro and in vivo, and enhances liver regeneration after partial hepatectomy.
Product Specifications
CAS Number
1414843-61-0
Purity
>98%
Smiles
C12=NC=C (C3=CNN=C3) N1C=CC (C1=CC=C (OC (C) C) C=C1) =C2
Molecular Formula
C19H18N4O
Molecular Weight
318.38
Storage Conditions
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Notes
For research use only.
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