LXR beta agonist 17
LXRβ agonist 17 is a novel, potent, orally active liver X receptor β (LXRβ) agonist with Ki/EC50 of 3/21 nM, displays 27-fold selectivity over LXRα; also exhibits excellent selectivity against other nuclear hormone receptors (>3,000-fold) ; induces the expression of LXR target genes in vitro and in vivo.
Product Specifications
CAS Number
1878259-00-7
Field of Research
Pharmacology & Drug Discovery
Purity
>98%
Smiles
S (C) (C1=C (CO) C=CC (=C1) N1CCN (C2N=CC (CO) =C (C (F) (F) F) N=2) [C@H] (C (C) C) C1) (=O) =O
Molecular Formula
C21H27F3N4O4S
Molecular Weight
488.52369427681
Notes
For research use only.
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