Pirinixic acid
Pirinixic acid (Wy-14643) is a potent agonist of PPARα, with EC50s of 0.63 μM, 32 μM for murine PPARα and PPARγ, and 5.0 μM, 60 μM, 35 μM for human PPARα, PPARγ and PPARδ, respectively.
Product Specifications
CAS Number
[50892-23-4]
Product Name Alternative
Wy-14643
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335, H350
Target
PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-anti-virus
Field of Research
Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Wy-14643.html
Purity
98.81
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(O)CSC1=NC(NC2=CC=CC(C)=C2C)=CC(Cl)=N1
Molecular Formula
C14H14ClN3O2S
Molecular Weight
323.80
Precautions
H302, H315, H319, H335, H350
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PPARα; PPARγ
Available Sizes
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