Myrislignan

Myrislignan, a lignan isolated from Myristica fragrans Houtt, possesses anti-inflammatory activities. Myrislignan attenuates LPS-induced inflammation reaction in murine macrophage cells through inhibition of NF-kB signalling pathway activation[1].

Product Specifications

CAS Number

[171485-39-5]

UNSPSC

12352005

Hazard Statement

H302

Target

NF-κB

Type

Natural Products

Related Pathways

NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/myrislignan.html

Purity

99.53

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

C[C@@H]([C@@H](C1=CC(OC)=C(O)C=C1)O)OC(C(OC)=CC(CC=C)=C2)=C2OC

Molecular Formula

C21H26O6

Molecular Weight

374.43

Precautions

H302

References & Citations

[1]Jin H, et al. Myrislignan attenuates lipopolysaccharide-induced inflammation reaction in murine macrophage cells through inhibition of NF-κB signalling pathway activation. Phytother Res. 2012 Sep;26 (9) :1320-6.