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Orantinib (TSU-68)

SU6668 has greatest potency against PDGFR autophosphorylation with Ki of 8 nM, but also strongly inhibits Flk-1 and FGFR1 trans-phosphorylation, little activity against IGF-1R, Met, Src, Lck, Zap70, Abl and CDK2; does not inhibit EGFR.

Product Specifications

CAS Number

252916-29-3

Purity

>98%

Smiles

C (O) (=O) CCC1C (C) =C (/C=C2/C3=C (NC/2=O) C=CC=C3) NC=1C

Molecular Formula

C28H26N4O4

Molecular Weight

482.53

Notes

For research use only.

Available Sizes

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