Orantinib (TSU-68)
SU6668 has greatest potency against PDGFR autophosphorylation with Ki of 8 nM, but also strongly inhibits Flk-1 and FGFR1 trans-phosphorylation, little activity against IGF-1R, Met, Src, Lck, Zap70, Abl and CDK2; does not inhibit EGFR.
Product Specifications
CAS Number
252916-29-3
Purity
>98%
Smiles
C (O) (=O) CCC1C (C) =C (/C=C2/C3=C (NC/2=O) C=CC=C3) NC=1C
Molecular Formula
C28H26N4O4
Molecular Weight
482.53
Notes
For research use only.
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