Suvorexant

(R) - (4- (5-Chlorobenzo[d]oxazol-2-yl) -7-methyl-1,4-diazepan-1-yl) (5-methyl-2- (2H-1,2,3-triazol-2-yl) phenyl) methanone; Suvorexant MK4305; MK 4305; MK-4305; Suvorexant (MK-4305) ; [ (7R) -4- (5-chloro-1,3-benzoxazol-2-yl) -7-methyl-1,4-diazepan-1-yl]-[5-methyl-2- (triazol-2-yl) phenyl]methanone;5-Chloro-2-[ (5R) -5-methyl-4-[5-methyl-2- (2H-1,2,3-triazol-2-yl) benzoyl]-1,4-diazepan-1-yl]-1,3-benzoxazole; Suvorexant; [ (7R) -4- (5-Chloro-1,3-benzoxazol-2-yl) -7-methyl-1,4-diazepan-1-yl][5-methyl-2- (2H-1,2,3-triazol-2-yl) phenyl]methanone; [ (R) -4- (5-chlorobenzooxazol-2-yl) -7-methyl-[1,4]diazepan-1-yl] (5-methy;5-chloro-2-{ (5R) -5-methyl-4-[5-methyl-2- (2H-1,2,3-triazol-2-yl) benzoyl]-1,4-diazepan-1-yl}-1,3-benzoxazole; Belsomra?; DORA-analogue; EOS-61934; SUVOREXABT; MK-4305 (Suvorexant) ; Synonyms Suvorexant; Suvorexant (with 4 ints.) ; BELSOMRA; MK4305;081L192FO9; C23H23ClN6O2; ((7R) -4- (5-Chloro-1,3-benzoxazol-2-yl) -7-methyl-1,4-diazepan-1-yl) (5-methyl-2- (2H-1,2,3-triazol-2-yl) phenyl) methanone; (R) - (4- (5-chlo

ClC1C ([H]) =C ([H]) C2=C (C=1[H]) N=C (N1C ([H]) ([H]) C ([H]) ([H]) N (C (C3C ([H]) =C (C ([H]) ([H]) [H]) C ([H]) =C ([H]) C=3N3N=C ([H]) C ([H]) =N3) =O) [C@] ([H]) (C ([H]) ([H]) [H]) C ([H]) ([H]) C1 ([H]) [H]) O2

Carlos Carrera-Cañas 1, Isabel de Andrés 1, Marta Callejo 1, Miguel Garzón 2 Hypocretin/orexin peptide release occurs mostly extrasynaptically, is self-controlled, and specifically enhanced in female rats Exp Neurol, (2025), Hiroki Endo et al. Dexamethasone induces sleep disruption in male mice and is associated with hyperactivation of orexin neurons Psychopharmacology (Berl) ., (2026), Gun Young Yoon et al. Disruption of the hypothalamic orexin system links SARS-CoV-2 infection to persistent cortical neuronal pathology bioRxiv, (2026)