ML314
Product Specifications
UNSPSC Description
ML314 is a potent molecule agonist of NTR1 (EC50 = 1.9 μM); showed good selectivity against NTR2 and GPR35, but does not stimulate Ca2+ mobilization.
Target Antigen
GPR35 ; Neurotensin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/ML314.html
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
COC1=CC=CC=C1N2CCN(C3=C4C=C(OC)C(OC)=CC4=NC(C5CC5)=N3)CC2
Molecular Weight
420.50
References & Citations
[1]Hershberger P, et al. Small Molecule Agonists for the Neurotensin 1 Receptor (NTR1 Agonists). Probe Reports from the NIH Molecular Libraries Program
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-16639/ML314-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-16639/ML314-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1448895-09-7
Available Sizes
Curated Selection
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