THPTA
THPTA is a water-soluble, very effective ligand for Cu (I) -catalyzed Alkyne-Azide click chemistry reactions (CuAAC) . It serves a dual purpose: 1) Accelaration of the CuAAC reaction by maintain-ing the Cu (I) oxidation state of copper sources and 2) Protection of biomolecules from oxidative damage during the labeling reaction. THPTA is a superior alternative to water-insoluble TBTA. A stock solution can be prepared in ddH 2O and subsequently be stored at -20C. Avoid freeze-thaw cycles.
Product Specifications
CAS Number
760952-88-3
Product Name Alternative
Tris ((1-hydroxy-propyl-1H-1,2,3-triazol-4-yl) methyl) amine
Purity
95% (HPLC)
Form
Solid; Color: off-white to grey
Solubility
Water, DMSO, DMF, MeOH
Smiles
N (Cc1nnn (c1) CCCO) (Cc1nnn (c1) CCCO) Cc1cn (nn1) CCCO
Molecular Formula
C18H30N10O3
Molecular Weight
Theoretical MW: 434.50 g/mol; Detected MW: 434.25 g/mol
Storage Conditions
Store at 4 °C
Notes
For research use only.
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