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8-Bromo-ATP

(8Br-ATP)

Product Specifications

CAS Number

81035-56-5

Product Name Alternative

(8Br-ATP), 8-Bromo-adenosine-5'-triphosphate, Sodium salt

Purity

≥ 95% (HPLC)

Form

Solid; Color: white to off-white

Smiles

Brc1n (c2c (n1) c (N) ncn2) [C@@H]1O[C@H] (COP (=O) (O) OP (=O) (O) OP (=O) (O) O) [C@@H] (O) [C@H]1O

Molecular Formula

C10H15N5O13P3Br

Molecular Weight

Theoretical MW: 586.08 g/mol (free acid) ; Detected MW: 584.91 g/mol (free acid)

Storage Conditions

Store at -20 °C

Notes

For research use only.

Applications Notes

Agonistic ligand, mainly for nucleoside receptor A1, with less affinity to A3 Nucleoside-triphosphates can be converted by different membrane-bound phosphatases into nucleosides acting as nucleoside receptor ligands. In some cases nucleoside phosphates act also directly on nucleoside receptors. Spectroscopic Propertie: λmax 264 nm, ε 17.0 L mmol-1 cm-1 (Tris-HCl, pH 7.5) . Specific Ligands: Ligand for purinergic receptors: P2Y2, P2X purinoreceptor.

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