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5-Aza-dCTP

5-Aza-dCTP is a inhibitor of DNA methylation and an antileukemic agent. It has been used to reactivate silent tumor suppressor genes.

Product Specifications

CAS Number

72052-96-1

Product Name Alternative

Decitabine triphosphate, 5-Aza-2'-deoxycytidine-5'-triphosphate, Sodium salt

Purity

≥ 95% (HPLC)

Form

Solid; Color: white to off-white

Smiles

O=P (O) (OP (=O) (OP (=O) (OC[C@@H]1[C@H] (C[C@H] (n2cnc (N) nc2=O) O1) O) O) O) O

Molecular Formula

C8H15N4O13P3

Molecular Weight

Theoretical MW: 468.14 g/mol (free acid) ; Detected MW: 467.98 g/mol (free acid)

Storage Conditions

Store at -20 °C

Notes

For research use only.

Applications Notes

Determination of methyltransferase activity. Spectroscopic Propertie: λmax 244 nm, ε 7.0 L mmol-1cm-1 (Tris-HCl, pH 7.5) . Specific Ligands: DNA-binding.
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