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B-GPP

B-GPP is a biotin-labeled analog of geranyl pyrophosphate (GPP) . It serves as lipid donor for the native RabGGTase and mutants of GGTase-I and FTase. B-GPP allows for straightforward mammalian prenylome labeling and thus, not only identifying protein prenyl-transferase substrates but efficiently screening for new inhibitors.

Product Specifications

Product Name Alternative

Biotin-labeled geranyl pyrophosphate, triethylammonium salt

Concentration

1 mM

Purity

Mass identification conforms (ESI-MS)

Form

Liquid (Supplied as 1 mM solution in 25 mM (NH 4) 2CO3)

Smiles

C1 (=O) N[C@@H]2[C@H] (N1) [C@@H] (SC2) CCCCC (=O) NC/C (=C/CC/C (=C/COP (=O) (O) OP (=O) (O) O) /C) /C

Molecular Formula

C20H35N3O9P2S

Molecular Weight

Theoretical MW: 555.52 g/mol

Storage Conditions

Store at -20 °C

Notes

For research use only.

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