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OGG1-IN-08

OGG1-IN-08 is a potent 8-oxoguanine DNA glycosylase-1 (OGG1) inhibitor with an IC50 value of 0.22 μM. OGG1-IN-08 decreases both the glycosylase and lyase activities of OGG1[1].

Product Specifications

CAS Number

350997-39-6

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/ogg1-in-08.html

Purity

99.60

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

O=C(C1=C(Cl)C2=C(Cl)C=CC=C2S1)NN

Molecular Formula

C9H6Cl2N2OS

Molecular Weight

261.13

Precautions

H315, H319, H335

References & Citations

[1]Nathan Donley, et al. Small Molecule Inhibitors of 8-Oxoguanine DNA Glycosylase-1 (OGG1) . ACS Chem Biol. 2015 Oct 16;10 (10) :2334-43.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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