OGG1-IN-08
OGG1-IN-08 is a potent 8-oxoguanine DNA glycosylase-1 (OGG1) inhibitor with an IC50 value of 0.22 μM. OGG1-IN-08 decreases both the glycosylase and lyase activities of OGG1[1].
Product Specifications
CAS Number
[350997-39-6]
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ogg1-in-08.html
Purity
99.60
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
O=C(C1=C(Cl)C2=C(Cl)C=CC=C2S1)NN
Molecular Formula
C9H6Cl2N2OS
Molecular Weight
261.13
Precautions
H315, H319, H335
References & Citations
[1]Nathan Donley, et al. Small Molecule Inhibitors of 8-Oxoguanine DNA Glycosylase-1 (OGG1) . ACS Chem Biol. 2015 Oct 16;10 (10) :2334-43.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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