4-Hydroxyacetophenone

4-Hydroxyacetophenone (P-hydroxyacetophenone) is a major hepatoprotective and choleretic compound found in Artemisia and Illicium plants, exhibiting antiviral and anti-inflammatory effects against hepatitis B virus. Additionally, 4-Hydroxyacetophenone inhibits cancer cell adhesion, invasion, and migration by remodeling actin. 4-Hydroxyacetophenone holds promise for research in the fields of inflammatory diseases and cancer[1][2].

Product Specifications

CAS Number

[99-93-4]

Product Name Alternative

P-hydroxyacetophenone

UNSPSC

12352005

Hazard Statement

H319, H412

Target

HBV; Myosin

Type

Natural Products

Related Pathways

Anti-infection; Cytoskeleton

Applications

COVID-19-anti-virus

Field of Research

Cancer; Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/4-hydroxyacetophenone.html

Concentration

10mM

Purity

99.99

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC(C1=CC=C(O)C=C1)=O

Molecular Formula

C8H8O2

Molecular Weight

136.15

Precautions

H319, H412

References & Citations

[1]Ching-Wen C, et al. p-Hydroxyacetophenone suppresses nuclear factor-κB-related inflammation in nociceptive and inflammatory animal models. J Nat Med. 2017 Apr;71 (2) :422-432.|[2]Bryan DS, et al. 4-Hydroxyacetophenone modulates the actomyosin cytoskeleton to reduce metastasis. Proc Natl Acad Sci U S A. 2020 Sep 8;117 (36) :22423-22429.