9-Octadecynoic acid

9-Octadecynoic acid is a DNA binding agent with a dissociation constant of 1.8 mM. 9-Octadecynoic acid is also an agonist for peroxisome proliferator-activated receptor γ (PPARγ) [1][2].

Product Specifications

CAS Number

[506-24-1]

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

PPAR

Type

Natural Products

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/9-octadecynoic-acid.html

Purity

99.90

Solubility

DMSO : 200 mg/mL (ultrasonic)

Smiles

O=C(CCCCCCCC#CCCCCCCCC)O

Molecular Formula

C18H32O2

Molecular Weight

280.45

Precautions

H302, H315, H319, H335

References & Citations

[1]Berry DE, et al. 9-Octadecynoic acid: a novel DNA binding agent. Chem Res Toxicol. 1991 Mar-Apr;4 (2) :195-8.|[2]Ohtera A, et al. Identification of 6-octadecynoic acid from a methanol extract of Marrubium vulgare L. as a peroxisome proliferator-activated receptor γ agonist. Biochem Biophys Res Commun. 2013 Oct 18;440 (2) :204-9.