Capsaicin (Purity 65%)

Capsaicin (Purity 65%) is a mixture of Capsaicin and Dihydrocapsaicin (Ratio >2:1) . Capsaicin (Purity 65%) is an orally active capsaicin receptor (TRPV1) agonist[1][2].

Product Specifications

CAS Number

[404-86-4]

UNSPSC

12352005

Hazard Statement

H300, H315, H317, H318, H334, H335

Target

Apoptosis; Autophagy; Endogenous Metabolite; TRP Channel

Type

Natural Products

Related Pathways

Apoptosis; Autophagy; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling

Applications

Cancer-Kinase/protease

Field of Research

Cancer; Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/capsaicin-purity-65.html

Purity

99.46

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC(C)/C=C/CCCCC(NCC1=CC=C(O)C(OC)=C1)=O

Molecular Formula

C18H27NO3

Molecular Weight

305.41

Precautions

H300, H315, H317, H318, H334, H335

References & Citations

[1]Hoyoun Cho, et al. Development of a database of capsaicinoid contents in foods commonly consumed in Korea. Food Sci Nutr. 2020 Jul 16;8 (8) :4611-4624.|[2]Krishnapura Srinivasan. Biological Activities of Red Pepper (Capsicum annuum) and Its Pungent Principle Capsaicin: A Review. Crit Rev Food Sci Nutr. 2016 Jul 3;56 (9) :1488-500.|[3]Zhang QH, et al. Effects of capsaicin and dihydrocapsaicin on human and rat liver microsomal CYP450 enzyme activities in vitro and in vivo. J Asian Nat Prod Res. 2012;14 (4) :382-95. |[4]Zhang Q, et al. Simultaneous quantification of capsaicin and dihydrocapsaicin in rat plasma using HPLC coupled with tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2010 Aug 15;878 (24) :2292-7.|[5]Joshi SK, et al Comparison of antinociceptive actions of standard analgesics in attenuating capsaicin and nerve-injury-induced mechanical hypersensitivity. Neuroscience. 2006 Dec 1;143 (2) :587-96.