Ac-YVAD-cmk
Ac-YVAD-cmk (Caspase-1 Inhibitor II) is a selective caspase-1 (IL-1beta converting enzyme, ICE) ) inhibitor with neuroprotective and anti-inflammatory effects. Ac-YVAD-cmk effectively suppresses the expression of IL-1β and IL-18. Ac-YVAD-cmk inhibits pyroptosis in many diseases[1][2].
Product Specifications
CAS Number
178603-78-6
Product Name Alternative
Caspase-1 Inhibitor II
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Caspase
Type
Reference compound
Related Pathways
Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ac-yvad-cmk.html
Purity
98.94
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC1=CC=C(C[C@H](NC(C)=O)C(N[C@H](C(N[C@@H](C)C(N[C@@H](CC(O)=O)C(CCl)=O)=O)=O)C(C)C)=O)C=C1
Molecular Formula
C24H33ClN4O8
Molecular Weight
540.99
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Caspase 1
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Von Willebrand Factor (3E2D10), CF740 conjugate, 0.1mg/mL
Eosinophil Peroxidase (AHE-1), CF740 conjugate, 0.1mg/mL
P27 / KIP1 (SX53G8), CF640R conjugate, 0.1mg/mL
