Glutaminase C-IN-1
Product Specifications
Product Name Alternative
Compound 968
UNSPSC Description
Glutaminase C-IN-1 (Compound 968) is an allosteric inhibitor of Glutaminase C that inhibits cancer cell growth without affecting their normal cellular counterparts[1][2].
Target Antigen
Glutaminase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Glutaminase-C-IN-1.html
Purity
99.88
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
O=C1C(C(C2=CC=C(N(C)C)C(Br)=C2)NC3=C4C5=CC=CC=C5C=C3)=C4CC(C)(C)C1
Molecular Weight
475.42
References & Citations
[1]Stalnecker CA, et al. Mechanism by which a recently discovered allosteric inhibitor blocks glutamine metabolism in transformed cells. Proc Natl Acad Sci U S A. 2015 Jan 13;112(2):394-9.|[2]Wang JB, et al. Targeting mitochondrial glutaminase activity inhibits oncogenic transformation. Cancer Cell. 2010 Sep 14;18(3):207-19.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-12682/Glutaminase-C-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-12682/Glutaminase-C-IN-1-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
311795-38-7
Available Sizes
Curated Selection
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