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PF-4840154

PF-4840154 is a non-electrophilic reference agonist of the TrpA1 channel. The TRPA1 channel is considered an attractive pain target based on the fact that TRPA1 knockout mice showed near complete attenuation of pain behaviors in some pre-clinical development models.

Product Specifications

CAS Number

1332708-14-1

Product Name Alternative

PF-4840154 | PF 4840154 | PF4840154

Purity

>98% (HPLC)

Solubility

DMSO : 50 mg/mL. 107.15 mM

Smiles

CC (C) CNc2nc (ncc2C (=O) NCc1ccccc1) N3CCN (CC3) CC4CCCOC4

Molecular Formula

C26H38N6O2

Molecular Weight

466.63

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

N-benzyl-4- (2-methylpropylamino) -2-[4- (oxan-3-ylmethyl) piperazin-1-yl] pyrimidine-5-carboxamide

Available Sizes

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