Lu AF21934
Lu AF21934 is a positive allosteric modulator of mGlu4 receptors. Lu AF21934 reduces the harmaline-induced hyperactivity but not tremor in rats. The actions of Lu AF21934 are 5-HT1A receptor-dependent. Activation of the mGlu4 receptor may be a promising mechanism for the development of novel antipsychotic drugs, efficacious toward positive, negative, and cognitive symptoms.
Product Specifications
CAS Number
1445605-23-1
Product Name Alternative
Lu AF21934 | Lu AF-21934 | Lu AF 21934
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 80 mg/mL. 253.81 mM
Smiles
C1CC[C@@H] ([C@@H] (C1) C (=O) N) C (=O) Nc1cc (c (cc1) Cl) Cl
Molecular Formula
C14H16Cl12N2O2
Molecular Weight
315.2
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(1S,2R) -N1- (3,4-Dichlorophenyl) cyclohexane-1,2-dicarboxamide
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