AZD7545
AZD7545 is an inhibitor of pyruvate dehydrogenase kinase 2 (PDHK2) (IC50 value of 6.4nM) for the treatment of type 2 diabetes. AZD7545 activates pyruvate dehydrogenase in vivo and improves blood glucose control in obese (fa/fa) Zucker rats.
Product Specifications
CAS Number
252017-04-2
Product Name Alternative
AZD7545 | AZD-7545 | AZD 7545
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 46 mg/mL; 96.06 mM
Smiles
O=C (N (C) C) c1ccc (S (=O) (=O) c2ccc (NC (=O) [C@@] (C) (O) C (F) (F) F) c (Cl) c2) cc1
Molecular Formula
C19H18ClF3N2O5S
Molecular Weight
478.87
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
4-[3-chloro-4-[[ (2R) -3,3,3-trifluoro-2-hydroxy-2-methylpropanoyl]amino]phenyl]sulfonyl-N, N-dimethylbenzamide
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