Roquinimex
Roquinimex, also known as LS 2616 and FCF89 (brande name: Linomide), is a quinoline-3-carboxamide with potential antineoplastic activity. Roquinimex inhibits endothelial cell proliferation, migration, and basement membrane invasion; reduces the secretion of the angiogenic factor tumor necrosis factor alpha by tumor-associated macrophages (TAMs) ; and inhibits angiogenesis. This agent is also an immune modulator that appears to alter cytokine profiles and enhance the activity of T cells, natural killer cells, and macrophages.
Product Specifications
CAS Number
84088-42-6
Product Name Alternative
FCF89 | FCF89 | LS 2616 | Linomide. US brand name: Linomide
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 83.3 mg/mL; 270.17 mM
Smiles
CN (c1ccccc1) C (=O) C3=C (O) c2ccccc2N (C) C3=O
Molecular Formula
C18H16N2O3
Molecular Weight
308.34
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
4-hydroxy-N,1-dimethyl-2-oxo-N-phenyl-1,2-dihydroquinoline-3-carboxamide
Available Sizes
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