BPTU
Allosteric antagonist of P2Y1 (EC50 = 0.06-0.3 μM) . Non-nucleotide ligand. Binds receptor outside of the helical bundle. Blocks inhibition of spontaneous contraction of rat and mouse colon induced by electrical field stimulation, nicotine and P2Y agonists. Antithrombotic; reduces platelet aggregation.
Product Specifications
CAS Number
870544-59-5
Product Name Alternative
BPTU | BMS-646786 | BMS 646786
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 33.3 mg/mL. 74.76 mM; H2O : < 0.1 mg/mL
Smiles
CC (C) (C) C1=CC=CC=C1OC2=C (C=CC=N2) NC (=O) NC3=CC=C (C=C3) OC (F) (F) F
Molecular Formula
C23H22F3N3O3
Molecular Weight
445.42
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
1-[2- (2-tert-Butylphenoxy) pyridin-3-yl]-3-[4- (trifluoromethoxy) phenyl]urea
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