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TCS 1102

TCS 1102 is a potent, dual orexin receptor antagonist (Ki values are 0.2 and 3 nM for OX2 and OX1 receptors respectively) . TCS 1102 inhibits ADL-orexin B-mediated locomotion following i.p. administration in vivo and blocks orexin-A (Cat.No.1455) mediated increases in feeding behaviour.

Product Specifications

CAS Number

916141-36-1

Product Name Alternative

TCS 1102, TCS1102, TCS-1102

Purity

>98% (HPLC)

Solubility

DMSO : ≥ 100 mg/mL; 212.50 mM

Smiles

Cn1c2ccccc2nc1SCC (=O) N1CCC[C@H]1C (=O) Nc1ccccc1c1ccccc1

Molecular Formula

C27H26N4O2S

Molecular Weight

470.59

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

(2S) -1-[2- (1-methylbenzimidazol-2-yl) sulfanylacetyl]-N- (2-phenylphenyl) pyrrolidine-2-carboxamide

Available Sizes

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