TCS 1102
TCS 1102 is a potent, dual orexin receptor antagonist (Ki values are 0.2 and 3 nM for OX2 and OX1 receptors respectively) . TCS 1102 inhibits ADL-orexin B-mediated locomotion following i.p. administration in vivo and blocks orexin-A (Cat.No.1455) mediated increases in feeding behaviour.
Product Specifications
CAS Number
916141-36-1
Product Name Alternative
TCS 1102, TCS1102, TCS-1102
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 100 mg/mL; 212.50 mM
Smiles
Cn1c2ccccc2nc1SCC (=O) N1CCC[C@H]1C (=O) Nc1ccccc1c1ccccc1
Molecular Formula
C27H26N4O2S
Molecular Weight
470.59
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(2S) -1-[2- (1-methylbenzimidazol-2-yl) sulfanylacetyl]-N- (2-phenylphenyl) pyrrolidine-2-carboxamide
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