Licochalcone D
Licochalcone D may be a potential drug for human melanoma treatment by inhibiting proliferation, inducing apoptosis via the mitochondrial pathway and blocking cell migration and invasion. Licochalcone D has cardioprotective potential against myocardial ischemia/reperfusion injury in langendorff-perfused rat hearts. Licochalcone D has anti-inflammatory activity, it shows suppression ability of nitric oxide (NO) production. Licochalcone D has anti-allergic activity, it suppresses degranulation by decreasing the intracellular Ca2+ level and tyrosine phosphorylation of ERK in RBL-2H3 cells.
Product Specifications
CAS Number
144506-15-0
Product Name Alternative
Licochalcone D | Licochalcone-D
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 125 mg/mL (352.71 mM)
Smiles
COc1c (O) c (O) ccc1\C=C\C (=O) c1ccc (O) c (CC=C (C) C) c1
Molecular Formula
C21H22O5
Molecular Weight
354.4
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(E) -3- (3,4-Dihydroxy-2-methoxyphenyl) -1-[4-hydroxy-3- (3-methylbut-2-enyl) phenyl]prop-2-en-1-one
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