EURYCOMANONE
Eurycomanone is cytotoxic on HepG2 cells by inducing apoptosis through the up-regulation of p53 and Bax, and down-regulation of Bcl-2.Eurycomanone has anti-cancer activity, inhibits A549 lung cancer cell proliferation in a dose-dependent manner at concentrations ranging from 5 to 20 μg/ml.
Product Specifications
CAS Number
84633-29-4
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 16.67 mg/mL (40.82 mM)
Smiles
CC1=CC (=O) [C@H] ([C@]2 ([C@H]1C[C@@H]3[C@]45[C@@H]2[C@] ([C@@H] (C (=C) [C@@]4 ([C@H] (C (=O) O3) O) O) O) (OC5) O) C) O
Molecular Formula
C20H28O11
Molecular Weight
444.43
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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