DPC 961
DPC 961 (DMP 961) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) . DPC 961 is a potent and specific inhibitor of HIV-1 reverse transcriptase, which inhibits the activity of HIV-1 reverse transcriptase in a non-competitive manner, thereby preventing viral replication. DPC 961 can be used for research on AIDS[1].
Product Specifications
CAS Number
214287-88-4
Product Name Alternative
(S) -DPC 961; DMP 961
UNSPSC
12352005
Target
HIV; Reverse Transcriptase
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/dpc-961.html
Smiles
FC(F)(F)[C@@]1(C2=CC(Cl)=CC=C2NC(N1)=O)C#CC3CC3
Molecular Formula
C14H10ClF3N2O
Molecular Weight
314.69
References & Citations
[1]Mutlib A, et al. Characterization of Novel Glutathione Adducts of a Non-Nucleoside Reverse Transcriptase Inhibitor, (S) -6-Chloro-4- (cyclopropylethynyl) -4- (trifluoromethyl) -3, 4-dihydro-2 (1 H) -quinazolinone (DPC 961), in Rats. Possible Formation of an Oxirene Metabolic Intermediate from a Disubstituted Alkyne[J]. Chemical research in toxicology, 2000, 13 (8) : 775-784.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
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