NPS2390
NPS2390 is a first generation quinoxaline derivative that acts as a noncompetitive antagonist of mGluR1 and mGluR5 (IC50 of 5.2 and 82 nM, respectively) . Treatment of NPS2390 was conducive to inhibit the proliferation and reverse phenotypic modulation of PASMCs by regulating autophagy levels.
Product Specifications
CAS Number
226878-01-9
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 6.25 mg/mL (20.33 mM)
Smiles
O=C (NC12CC3CC (CC (C3) C1) C2) c1cnc2ccccc2n1
Molecular Formula
C19H21N3O
Molecular Weight
307.4
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Available Sizes
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