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NPS2390

NPS2390 is a first generation quinoxaline derivative that acts as a noncompetitive antagonist of mGluR1 and mGluR5 (IC50 of 5.2 and 82 nM, respectively) . Treatment of NPS2390 was conducive to inhibit the proliferation and reverse phenotypic modulation of PASMCs by regulating autophagy levels.

Product Specifications

CAS Number

226878-01-9

Purity

>98% (HPLC)

Solubility

In Vitro: DMSO : 6.25 mg/mL (20.33 mM)

Smiles

O=C (NC12CC3CC (CC (C3) C1) C2) c1cnc2ccccc2n1

Molecular Formula

C19H21N3O

Molecular Weight

307.4

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Available Sizes

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