MTEP hydrochloride
MTEP hydrochloride is non-competitive mGlu5 antagonist (IC50 and Ki of 5 nM and 16 nM respectively) . (In Vitro) :MTEP shows highly selective for mGluR5 over mGluR1, has no effect on other mGluR subtypes, and has fewer off-target effects than MPEP (HY-14609A) . (In Vivo) :MTEP (0-5 mg/kg, i.p., once) inhibits the catalepsy induced by Haloperidol (HY-14538) (0.5 mg/kg/2 ml i.p.) .MTEP (0.3-3 mg/kg, intraperitoneal injection, once) induces antidepressant-like effects in male C57BL/6J mice.
Product Specifications
CAS Number
1186195-60-7
Product Name Alternative
3- ((2-Methyl-13-thiazol-4-yl) ethyn-yl) pyridine hydrochloride | MTEP
Purity
>98% (HPLC)
Solubility
H2O:20 mg/mL (84.49 mM; Need ultrasonic)
Smiles
Cc1nc (C#Cc2cccnc2) cs1.Cl
Molecular Formula
C11H9ClN2S
Molecular Weight
236.72
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
3- ((2-Methyl-13-thiazol-4-yl) ethynyl) pyridine hydrochloride
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