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VU591

VU591 is the first reported selective, small-molecule ROMK inhibitor (IC50 of 0.24 μM) . It inhibits potassium transport in isolated perfused rat collecting duct tubules with no effect on sodium transport.

Product Specifications

CAS Number

1222810-74-3

Purity

>98% (HPLC)

Solubility

DMSO:60 mg/mL (162.91 mM; Need ultrasonic)

Smiles

[O-][N+] (=O) c1ccc2nc (COCc3nc4ccc (cc4[nH]3) [N+] ([O-]) =O) [nH]c2c1

Molecular Formula

C16H12N6O5

Molecular Weight

368.3

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

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