Spaglumic acid
Spaglumic acid is a neuropeptide found in millimolar concentrations in the brain.Spaglumic Acid is released upon depolarization by a Ca2+-dependent process and is an agonist at mGluR3 receptors and an antagonist at NMDA receptors. Spaglumic Acid is catabolized to N-acetylaspartate and glutamate primarily by glutamate carboxypeptidase II, which is expressed on the extracellular surface of astrocytes.
Product Specifications
CAS Number
3106-85-2
Product Name Alternative
NAAG, N-Acetylaspartylglutamic acid
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
Water:29 mg/mL (95.31 mM)
Smiles
CC (=O) N[C@@H] (CC (O) =O) C (=O) N[C@@H] (CCC (O) =O) C (O) =O
Molecular Formula
C11H16N2O8
Molecular Weight
304.26
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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